Paul A Dawson Selected Research

1- (4- (4- (3,3- dibutyl- 7- (dimethylamino)- 2,3,4,5- tetrahydro- 4- hydroxy- 1,1- dioxido- 1- benzothiepin- 5- yl)phenoxy)butyl)- 4- aza- 1- azoniabicyclo(2.2.2)octane

1/2020	Attenuation of the Hepatoprotective Effects of Ileal Apical Sodium Dependent Bile Acid Transporter (ASBT) Inhibition in Choline-Deficient L-Amino Acid-Defined (CDAA) Diet-Fed Mice.
1/2016	Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice.

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Paul A Dawson Research Topics

Disease

5	Liver Diseases (Liver Disease) 01/2019 - 06/2010
4	Hypercholesterolemia 12/2021 - 06/2013
4	Non-alcoholic Fatty Liver Disease 10/2020 - 01/2016
4	Diarrhea 01/2018 - 09/2003
3	Cholestasis 04/2014 - 04/2002
2	Obesity 12/2021 - 10/2020
2	Autism Spectrum Disorder 10/2021 - 01/2018
2	Autistic Disorder (Autism) 01/2018 - 02/2013
2	Steatorrhea 01/2018 - 09/2003
2	Inflammation (Inflammations) 07/2016 - 08/2006
2	Colonic Neoplasms (Colon Cancer) 10/2015 - 05/2006
2	Atherosclerosis 01/2015 - 08/2013
2	Urolithiasis 01/2013 - 03/2010
2	Nephrocalcinosis 01/2013 - 03/2010
2	Hyperoxaluria (Oxaluria) 01/2013 - 03/2010
1	Seizures (Absence Seizure) 01/2022
1	Metabolic Diseases (Metabolic Disease) 10/2020
1	Kallmann Syndrome (Kallmann's Syndrome) 06/2020
1	Body Weight (Weight, Body) 01/2020
1	Fibrosis (Cirrhosis) 01/2020
1	Avitaminosis (Vitamin Deficiency) 01/2018
1	Insulin Resistance 01/2017
1	Sclerosing Cholangitis 02/2016
1	Fatty Liver 01/2016
1	Neoplasms (Cancer) 10/2015
1	Carcinogenesis 10/2015
1	Aberrant Crypt Foci 10/2015
1	Hemorrhage 02/2015
1	Cardiovascular Diseases (Cardiovascular Disease) 06/2013
1	Short Bowel Syndrome 07/2012
1	Atelosteogenesis type 2 08/2011
1	Achondrogenesis type 1B 08/2011
1	Diastrophic dysplasia 08/2011
1	Mesomelia-synostoses syndrome 08/2011
1	Chondrodysplasia Punctata (Stippled Epiphyses) 08/2011
1	Dwarfism 08/2011
1	Osteochondrodysplasias (Spondyloepiphyseal Dysplasia) 08/2011
1	Intrahepatic Cholestasis 06/2010
1	Acute Liver Failure (Fulminant Hepatic Failure) 03/2010
1	Urinary Calculi (Urinary Calculus) 03/2010
1	Ileitis 08/2006
1	Liver Failure 06/2006

Drug/Important Bio-Agent (IBA)

19	Bile Acids and Salts (Bile Acids)IBA 12/2021 - 04/2002
7	CholesterolIBA 12/2021 - 02/2003
6	Sulfates (Sulfates, Inorganic)IBA 01/2022 - 06/2006
3	Proteins (Proteins, Gene)FDA Link 01/2013 - 07/2005
2	Biological ProductsIBA 10/2021 - 01/2018
2	sodium-bile acid cotransporterIBA 01/2020 - 01/2017
2	Triglycerides (Triacylglycerol)IBA 01/2020 - 01/2016
2	1- (4- (4- (3,3- dibutyl- 7- (dimethylamino)- 2,3,4,5- tetrahydro- 4- hydroxy- 1,1- dioxido- 1- benzothiepin- 5- yl)phenoxy)butyl)- 4- aza- 1- azoniabicyclo(2.2.2)octaneIBA 01/2020 - 01/2016
2	Primary Bile Acid MalabsorptionIBA 01/2018 - 09/2003
2	bile acid binding proteinsIBA 07/2016 - 09/2003
2	Indomethacin (Indometacin)FDA LinkGeneric 02/2015 - 08/2006
2	Apolipoproteins E (ApoE)IBA 01/2015 - 08/2013
2	Calcium OxalateIBA 01/2013 - 03/2010
2	AnionsIBA 01/2013 - 03/2010
2	Acetaminophen (Paracetamol)FDA LinkGeneric 03/2010 - 06/2006
1	Ezetimibe (Zetia)FDA Link 12/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2020
1	Nonsense Codon (Nonsense Mutation)IBA 06/2020
1	Choline (Choline Chloride)IBA 01/2020
1	Amino Acids FDA Link 01/2020
1	CDAA (Randox)IBA 01/2020
1	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2018
1	RNA (Ribonucleic Acid)IBA 07/2016
1	SteroidsIBA 07/2016
1	SodiumIBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	AzoxymethaneIBA 10/2015
1	CarcinogensIBA 10/2015
1	ErbB Receptors (EGF Receptor)IBA 10/2015
1	Cholinergic Agents (Cholinergics)IBA 10/2015
1	Dextran SulfateIBA 10/2015
1	Phosphotransferases (Kinase)IBA 10/2015
1	Analgesics (Analgesic Drugs)IBA 02/2015
1	Pharmaceutical PreparationsIBA 02/2015
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 02/2015
1	Apolipoproteins B (ApoB)IBA 01/2015
1	LDL Receptors (LDL Receptor)IBA 01/2015
1	Sirtuin 1IBA 04/2014
1	Indicators and Reagents (Reagents)IBA 04/2014
1	Fish OilsIBA 07/2012
1	SulfatasesIBA 08/2011
1	Sulfate TransportersIBA 08/2011
1	Proteoglycans (Proteoglycan)IBA 08/2011
1	SulfotransferasesIBA 08/2011
1	OxalatesIBA 03/2010
1	Cholestyramine Resin (Questran)FDA LinkGeneric 12/2006
1	XenobioticsIBA 06/2006
1	Messenger RNA (mRNA)IBA 05/2006
1	Chenodeoxycholic Acid (Chenix)FDA Link 05/2006
1	Cholic AcidIBA 05/2006
1	salicylhydroxamic acid (SHAM)IBA 07/2005
1	bilirubin glucuronateIBA 07/2005
1	Etoposide (VP 16)FDA LinkGeneric 07/2005
1	EnzymesIBA 05/2005

Therapy/Procedure

3	Therapeutics 01/2018 - 01/2016
1	Analgesia 04/2014
1	Nephrectomy 01/2013
1	Ligation 07/2005